PUBLICATIONS

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Localized low-dose rhBMP-2 is effective at promoting bone regeneration in mandibular segmental defects

 Drug Delivery

 In vivo Pig 

 Micro CT 

 Bone Regeneration 

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Carlisle PL, Guda T, Silliman DT , Hale RG, BrownBaer PR.

Are critical size bone notch defects possible in the rabbit mandible?

 Biomechanics 

 In vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Pearson JJ, Ortiz AS, Montelongo S, Simpson CB, Guda T, Dion GR

Quantification of injection force mechanics during injection laryngoplasty

 Biomechanics 

 Ex vivo Pig 

 Indentation 

 Vocal Folds 

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Burdette AJ, Guda T, Thompson ME, Banas R, Sheppard F

J Craniofac Surg. 2018 Jan; 29(1):116-123.

A Novel Secretome Biotherapeutic Influences Regeneration in Critical Size Bone Defects

 Extracellular Matrix 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

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Pollot BE, Rathbone CR, Wenke JC, Guda T.

J Biomed Mater Res B Appl Biomater. 2018 Feb; 106(2):672-679.

Natural polymeric hydrogel evaluation for skeletal muscle tissue  engineering

 Biomechanics 

 Ex vivo Pig

 Indentation 

 Muscle Engineering

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Habibi N, Pastorino L, Babolmorad G, Ruggiero C, Guda T, Ong JL.

J Drug Deliv Sci Technol, 2017 Apr; 38:1-8.

Polyelectrolyte multilayers and capsules: S-layer functionalization for improving stability and biocompatibility

 Drug Delivery 

 In Vitro 

 Characterization 

 Biomaterials 

Gaviria L, Pearson JJ, Montelongo SA, Guda T, Ong JL.

J Korean Assoc Oral Maxillofac Surg. 2017 Oct; 43(5):288-298.

Three-dimensional printing for craniomaxillofacial regeneration

 3D Printing 

 Review 

 Characterization 

 Dental Engineering 

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Mater Sci Eng C Mater Biol Appl. 2016 Nov; 68:723-731.

Hydroxyapatite coating on PEEK implants: Biomechanical and histological study in a rabbit model

 Biomechanics 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Carlisle PL, Guda T, Silliman DT, Lien W, Hale RG, Brown Baer PR

J Korean Assoc Oral Maxillofac Surg. 2016 Feb; 42(1):20-30.

Investigation of a pre-clinical mandibular bone notch defect model in miniature pigs: clinical computed tomography, micro-computed tomography, and histological evaluation

 Correlation

 In Vivo Pig 

 Micro CT 

 Bone Regeneration 

Pilia M, Murray M, Guda T, Heckman M, Appleford M

Orthopedics. 2015 Jul; 38(7): e582-7.

Pretensioning of Soft-Tissue Grafts in Anterior Cruciate Ligament Reconstruction

 Biomechanics 

 Ex Vivo Human 

 Strength 

 Tendons Ligaments 

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Konofaos P, Petersen D, Jennings JA, Smith RA, Doty H, Reves BT, Guda T, Appleford MR, Bumgardner JD, Wallace RD

J Craniofac Surg. 2015 Jun; 26(4):1408-12

Evaluation of Amniotic Multipotential Tissue Matrix to Augment Healing of Demineralized Bone Matrix in an Animal Calvarial Model

 Extracellular Matrix 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

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Dadsetan M, Guda T, Runge MB, Mijares D, LeGeros RZ, LeGeros JP, Silliman DT, Lu L, Wenke JC, Brown Baer PR, Yaszemski MJ

Acta Biomater. 2015 May; 18:9-20.

Effect of calcium phosphate coating and rhBMP-2 on bone regeneration in rabbit calvaria using poly (propylene fumarate) scaffolds

 Drug Delivery 

 In Vivo Rabbit  

 Micro CT 

 Bone Regneration 

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Xu H, Gu S, Riquelme MA, Burra S, Callaway D, Cheng H, Guda T, Schmitz J, Fajardo RJ, Werner SL, Zhao H, Shang P, Johnson ML, Bonewald LF, Jiang JX.

J Bone Miner Res. 2015 Mar; 30(3):436-48. 

Connexin 43 Hemichannels are Essential for Normal Bone Structure and Osteocyte Viability

 Molecular Biology 

 In Vivo Mouse 

 Micro CT 

 Bone Matrix 

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Kim S, Bedigrew K, Guda T, Maloney WJ, Park S, Wenke JC, Yang YP.

Acta Biomater. 2014 Dec; 10(12):5021-5033.

Novel osteoinductive photo-cross-linkable chitosan-lactide-fibrinogen (CLF) hydrogels enhanced bone regeneration in critical size segmental bone defects

 Drug Delivery 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

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Pilia M, McDaniel JS, Guda T, Chen XK, Rhoads RP, Allen RE, Corona BT, Rathbone CR.

Eur Cell Mater. 2014 Jul; 28:11-23; discussion 23-4.

Transplantation and perfusion of microvascular fragments in a rodent model of volumetric muscle loss injury

 Biologic Delivery 

 In vivo Rat 

 Vascularization 

 Muscle Engineering

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Shah AR, Cornejo A, Guda T, Sahar DE, Stephenson SM, Chang S, Krishnegowda NK, Sharma R, Wang HT.

J Craniofac Surg. 2014 Jul; 25(4):1504-9.

Differentiated adipose-derived stem cell co-cultures for bone regeneration in polymer scaffolds in vivo

 Biologic Delivery 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

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Guda T, Labella C, Chan R, Hale R.

Wound Repair Regen. 2014 May; 22 Suppl 1:39-49.

Quality of bone healing: perspectives and assessment techniques

 Extracellular Matrix 

 Review 

 Characterization 

 Bone Regeneration 

Rathbone CR, Guda T, Singleton BM, Oh DS, Appleford MR, Ong JL, Wenke JC.

J Biomed Mater Res A. 2014 May; 102(5):1458-66.

Effect of hydroxyapatite scaffolds seeded with cells on in vivo bone regeneration

 Biologic Delivery 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Gaviria L, Salcido JP, Guda T, Ong JL.

Current trends in dental implants

 Drug Delivery 

 Review 

 Characterization 

 Dental Engineering 

Sharma R, Callaway D, Vanegas D, Bendele M, Lopez-Cruzan M, Horn D, Guda T, Fajardo R, Abboud-Werner S, Herman B.

PLoS One. 2014 Apr; 9(4):e93696.

Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts

 Biomechanics 

 In Vivo Mouse 

 Micro CT 

 Bone Matrix 

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Guda T, Walker JA, Singleton B, Hernandez J, Oh DS, Appleford MR, Ong JL, Wenke JC.

J Biomater Appl. 2014 Mar; 28(7):1016-27.

Hydroxyapatite scaffold pore architecture effects in large bone defects in vivo

 Drug Delivery 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Guda T, Darr A, Silliman DT, Magno MH, Wenke JC, Kohn J, Brown Baer PR.

Tissue Eng Part C Methods. 2014 Sep; 20(9):749-60.

Methods to analyze bone regenerative response to different rhBMP-2 doses in rabbit craniofacial defects

 Correlation 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Burns TC, Barrow AE, Pilia M, Guda T, Kadrmas WR.

Am J Sports Med. 2014 Feb;42(2):NP16-8.

Femoral Suspension Devices for Anterior Cruciate Ligament Reconstruction: Letter to the Editor/Response

 Biomechanics 

Medical Device 

 Strength 

 Tendons Ligaments 

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Pilia M, Guda T, Pollot BE, Aguero V, Appleford MR.

Mater Sci Eng C Mater Biol Appl. 2014 Feb 1;35:122-33.

Local microarchitecture affects mechanical properties of deposited extracellular matrix for osteonal regeneration

 Extracellular Matrix 

 In Vitro 

 Characterization 

 Biomaterials 

Barrow AE, Pilia M, Guda T, Kadrmas WR, Burns TC.

Am J Sports Med. 2014 Feb; 42(2):343-9.

Femoral Suspension Devices for Anterior Cruciate Ligament Reconstruction: Do Adjustable Loops Lengthen?

 Biomechanics 

 Medical Device 

 Strength 

 Tendons Ligaments 

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Dumas JE, Prieto EM, Zienkiewicz KJ, Guda T, Wenke JC, Bible J, Holt GE, Guelcher SA.

Tissue Eng Part A. 2014 Jan;20(1-2):115-29.

Balancing the Rates of New Bone formation and Polymer Degradation Enhances Healing of Weight-Bearing Allograft/Polyurethane Composites in Rabbit Femoral Defects

 Extracellular Matrix 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

Pilia M, Guda T, Shiels SM, Appleford MR.

J Biol Eng. 2013 Oct 3;7(1):23.

Influence of substrate curvature on osteoblast orientation and extracellular matrix deposition

 Extracellular Matrix 

 In Vitro 

 Characterization 

 Biomaterials 

Witek L, Smay J, Silva NRFA, Guda T, Ong JL, Coelho PG.

J Adv Ceram, 2013 Sep; 2(3):274-284.

Sintering Effects on Physical and Chemical Properties of Extruded Bioactive Ceramic Rods

 Biomechanics 

 Medical Device 

 Characterization 

 Biomaterials 

Guda T, Walker JA, Singleton BM, Hernandez JW, Son JS, Kim SG, Oh DS, Appleford MR, Ong JL, Wenke JC.

Tissue Eng Part A. 2013 Sep; 19(17-18):1879-88.

Guided Bone Regeneration in Long-Bone Defects with a Structural Hydroxyapatite Graft and Collagen Membrane

 Architecture 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Actis L, Gaviria L, Guda T, Ong JL.

Antimicrobial Surfaces for Craniofacial Implants: State of the art

 Drug Delivery 

 Review 

 Characterization 

 Dental Engineering 

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Pilia M, Guda T, Appleford M.

Biomed Res Int. 2013; 2013:458253.

Development of Composite Scaffolds for Load Bearing Segmental Bone Defects

 Biomechanics 

 Review 

 Characterization 

 Biomaterials 

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Shiels S, Oh S, Bae C, Guda T, Singleton B, Dean DD, Wenke JC, Appleford MR, Ong JL.

J Biomed Mater Res B Appl Biomater. 2012 Oct; 100(7):1782-91.

Evaluation of BMP-2 tethered polyelectrolyte coatings on HAp scaffolds in vivo

 Drug Delivery 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Cornejo A, Sahar DE, Stephenson SM, Chang S, Nguyen S, Guda T, Wenke JC, Vasquez A, Michalek JE, Sharma R, Krishnegowda NK, Wang HT.

Tissue Eng Part A. 2012 Aug; 18(15-16):1552-61.

Effect of Adipose Tissue-Derived Osteogenic and Endothelial Cells on Bone Allograft Osteogenesis and Vascularization in Critical-Sized Calvarial Defects

 Biologic Delivery 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

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Dumas JE, BrownBaer PB, Prieto EM, Guda T, Hale RG, Wenke JC, Guelcher SA.

Biomed Mater. 2012 Apr; 7(2):024112.

Injectable Reactive Biocomposites for Bone Healing in Critical-size Rabbit Calvarial Defects

 Architecture 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Guda T, Oh S, Appleford MR, Ong JL.

Int J Oral Maxillofac Implants. 2012 Mar-Apr; 27(2):288-94.

Bilayer hydroxyapatite scaffolds for maxillofacial bone tissue engineering

 Architecture 

 In Vitro 

 Micro CT 

 Biomaterials 

Guelcher SA, Brown KV, Li B, Guda T, Lee BH, Wenke JC.

J Orthop Trauma. 2011 Aug; 25(8):477-82.

Dual-Purpose Bone Grafts Reduce Infection and Improve Healing

 Drug Delivery 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

Brown KV, Li B, Guda T, Perrien DS, Guelcher SA, Wenke JC.

Tissue Eng Part A. 2011 Jul; 17(13-14):1735-46.

Improving bone formation in a rat femur segmental defect by controlling BMP-2 release

 Drug Delivery 

 In vivo Rat 

 Micro CT 

 Bone Regeneration 

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Guda T, Walker JA, Pollot BE, Appleford MR, Oh S, Ong JL, Wenke JC.

J Mater Sci Mater Med. 2011 Mar;22(3):647-56.

In vivo performance of bilayer hydroxyapatite scaffolds for bone tissue regeneration in the rabbit radius model

 Architecture 

 In Vivo Rabbit 

 Micro CT 

 Bone Regeneration 

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Dong XN, Guda T, Millwater HR, Wang X.

J Biomech. 2009 Feb 9; 42(3):202-9.

Probabilistic failure analysis of bone using a finite element model of mineral-collagen composites

 Biomechanics 

 In Silico 

 Strength 

 Bone Matrix 

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Chesnutt BM, Viano AM, Yuan Y, Yang Y, Guda T, Appleford MR, Ong JL, Haggard WO, Bumgardner JD.

J Biomed Mater Res A. 2009 Feb; 88(2):491-502.

Design and Characterization of a Novel Chitosan/ Nanocrystalline Calcium Phosphate Composite Scaffold for Bone Regeneration

 Architecture 

 In Vitro 

 Micro CT 

 Biomaterials 

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Son J-S, Guda T, Appleford M, Ong JL, Park K, Han D-K, Oh S.

Tissue Eng Regen Med. 2009; 6(13):1241-1251.

Structure and characteristics of Novel Hydroxyapatite/Polylactide Bi-layered Porous Scaffold for Bone Regeneration

 Architecture 

 In Vitro 

 Micro CT 

 Biomaterials 

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Guda T, Ross TA, Lang LA, Millwater HR.

J Prosthet Dent. 2008 Sep; 100(3):183-93.

Probabilistic analysis of preload developed in dental implant abutment screws

 Biomechanics 

 In Silico 

 Strength 

 Dental Engineering 

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Guda T, Appleford M, Oh S, Ong JL.

Curr Top Med Chem. 2008; 8(4):290-9.

A cellular perspective to bioceramic scaffolds for bone tissue engineering: the state of the art

 Biomechanics 

 Review 

 Characterization 

 Biomaterials 

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The University of Texas at San Antonio

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